Imuran

General information

Imuran is a generic drug that is prescribed for rheumatoid arthritis and other conditions in adults. It is also used to prevent rejection of transplanted organs. It is available as the brand-name drugs Imuran and Azasan. Imuran belongs to a class of drugs known as immunosuppressants; It works by suppressing the immune system, which helps to reduce inflammation and prevent rejection of transplanted organs. Imuran is available in tablet form and is usually taken once or twice a day. The dosage of Imuran will vary depending on the individual patient and the condition being treated.

Use

Imuran is used to treat a variety of conditions, including⁚
  • Rheumatoid arthritis
  • Crohn's disease
  • Ulcerative colitis
  • Psoriasis
  • Lupus
  • Multiple sclerosis
  • Myasthenia gravis
  • Organ transplant rejection
Imuran is an immunosuppressant, which means that it suppresses the immune system. This can be helpful in treating conditions that are caused by an overactive immune system, such as rheumatoid arthritis and Crohn's disease. Imuran can also be used to prevent rejection of transplanted organs. Imuran is typically taken once or twice a day, with or without food. The dosage of Imuran will vary depending on the individual patient and the condition being treated. It is important to take Imuran exactly as prescribed by your doctor. Imuran can be effective in treating a variety of conditions, but it is important to be aware of the potential side effects. These side effects can include⁚
  • Nausea
  • Vomiting
  • Diarrhea
  • Hair loss
  • Skin rash
  • Increased risk of infection
If you experience any of these side effects, it is important to talk to your doctor. In some cases, the dosage of Imuran may need to be adjusted or the medication may need to be discontinued. Overall, Imuran is a safe and effective medication for treating a variety of conditions. However, it is important to be aware of the potential side effects and to talk to your doctor if you experience any problems.

Dosage

The dosage of Imuran will vary depending on the individual patient and the condition being treated. The following are the usual dosages for adults⁚
  • Rheumatoid arthritis⁚ 1-2.5 mg/kg/day
  • Crohn's disease⁚ 2-2.5 mg/kg/day
  • Ulcerative colitis⁚ 1-2 mg/kg/day
  • Psoriasis⁚ 1-2.5 mg/kg/day
  • Lupus⁚ 1-2 mg/kg/day
  • Multiple sclerosis⁚ 1-2 mg/kg/day
  • Myasthenia gravis⁚ 2-3 mg/kg/day
  • Organ transplant rejection⁚ 3-5 mg/kg/day
Imuran is typically taken once or twice a day, with or without food. It is important to take Imuran exactly as prescribed by your doctor. The dosage of Imuran may need to be adjusted if you have certain medical conditions, such as kidney or liver disease. Your doctor will monitor your blood counts and liver function regularly to ensure that the medication is not causing any problems. If you miss a dose of Imuran, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Imuran at the same time. It is important to take Imuran for the full course of treatment, even if you start to feel better. Stopping Imuran too early can lead to a flare-up of your condition. If you have any questions about the dosage of Imuran, talk to your doctor or pharmacist.

Interactions

Imuran can interact with a number of other medications, including⁚
  • Allopurinol⁚ Allopurinol can increase the levels of Imuran in the blood, which can lead to an increased risk of side effects.
  • Mercaptopurine⁚ Mercaptopurine is a similar medication to Imuran, and it can also interact with Imuran to increase the risk of side effects.
  • Azathioprine⁚ Azathioprine is another similar medication to Imuran, and it can also interact with Imuran to increase the risk of side effects.
  • Ciclosporin⁚ Ciclosporin can increase the levels of Imuran in the blood, which can lead to an increased risk of side effects.
  • Tacrolimus⁚ Tacrolimus can increase the levels of Imuran in the blood, which can lead to an increased risk of side effects.
  • Methotrexate⁚ Methotrexate can interact with Imuran to increase the risk of side effects, such as bone marrow suppression.
  • Live vaccines⁚ Live vaccines can be dangerous for people who are taking Imuran, as they can cause serious infections.
It is important to tell your doctor about all of the medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements. This will help your doctor to determine if Imuran is safe for you to take. If you are taking any of the medications listed above, your doctor may need to adjust your dosage of Imuran or monitor you more closely for side effects. In addition to the medications listed above, Imuran can also interact with certain foods and beverages. For example, grapefruit juice can increase the levels of Imuran in the blood, which can lead to an increased risk of side effects. It is important to avoid grapefruit juice while taking Imuran. If you have any questions about the interactions of Imuran, talk to your doctor or pharmacist.

Side effects

Imuran can cause a number of side effects, including⁚
  • Nausea
  • Vomiting
  • Diarrhea
  • Hair loss
  • Skin rash
  • Increased risk of infection
  • Bone marrow suppression
  • Liver damage
  • Kidney damage
  • Cancer
The most common side effects of Imuran are nausea, vomiting, and diarrhea. These side effects are usually mild and go away within a few weeks. However, if you experience any of these side effects, it is important to talk to your doctor. Imuran can also cause more serious side effects, such as bone marrow suppression, liver damage, and kidney damage. These side effects are rare, but they can be life-threatening. If you experience any of these side effects, it is important to seek medical attention immediately. Imuran can also increase the risk of developing cancer. The risk of cancer is small, but it is important to be aware of this potential side effect. If you are concerned about the side effects of Imuran, talk to your doctor. Your doctor can help you to weigh the risks and benefits of Imuran and decide if it is the right medication for you.

Contraindications

Imuran is contraindicated in patients who are allergic to azathioprine or any of the other ingredients in the medication. Imuran is also contraindicated in patients who have severe liver disease or kidney disease. Imuran should be used with caution in patients who have a history of bone marrow suppression or who are taking other medications that can suppress the bone marrow. Imuran can also increase the risk of developing cancer, so it should be used with caution in patients who have a history of cancer or who are at high risk for developing cancer. Imuran is not recommended for use in children under the age of 2 years. If you are pregnant or planning to become pregnant, talk to your doctor before taking Imuran. Imuran can cause birth defects, so it is important to weigh the risks and benefits of the medication before taking it during pregnancy. Imuran can also pass into breast milk, so it is not recommended for use in women who are breastfeeding. If you have any questions about the contraindications of Imuran, talk to your doctor.

Overdose

An overdose of Imuran can be fatal. Symptoms of an overdose can include⁚
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Headache
  • Dizziness
  • Confusion
  • Seizures
  • Coma
If you think that you or someone else has overdosed on Imuran, call 911 immediately. Do not wait for symptoms to develop. Treatment for an overdose of Imuran may include⁚
  • Gastric lavage
  • Activated charcoal
  • Intravenous fluids
  • Blood transfusions
  • Bone marrow transplant
The prognosis for an overdose of Imuran depends on the severity of the overdose and the promptness of treatment. If you have any questions about the overdose of Imuran, talk to your doctor or pharmacist.

Storage

Imuran should be stored at room temperature, between 59°F and 86°F (15°C and 30°C). Imuran should be protected from light and moisture. Do not store Imuran in the bathroom or in other areas where it could be exposed to heat or moisture. Keep Imuran out of the reach of children and pets. If you have any questions about the storage of Imuran, talk to your doctor or pharmacist.

Availability

Imuran is available as a generic medication and as the brand-name medication Imuran. Imuran is available in tablet form and injectable form. Imuran is a prescription medication, which means that it can only be obtained with a prescription from a doctor. Imuran is typically covered by most insurance plans. If you have any questions about the availability of Imuran, talk to your doctor or pharmacist.

Cost

The cost of Imuran will vary depending on the dosage and form of the medication, as well as the pharmacy where you fill your prescription. As of 2023, the average cost of a 50-mg tablet of Imuran is about $10 per tablet. A 100-mg tablet of Imuran costs about $20 per tablet. If you have insurance, your copay for Imuran will vary depending on your insurance plan. You may also be able to get a discount on Imuran if you use a prescription discount card. If you are uninsured or underinsured, there are a number of programs that can help you to get free or low-cost Imuran. The following are some tips for saving money on Imuran⁚
  • Use a prescription discount card.
  • Ask your doctor about generic Imuran.
  • Buy Imuran in bulk.
  • Shop around for the best price.
If you have any questions about the cost of Imuran, talk to your doctor or pharmacist.

Brand names

Imuran is the brand name for the generic medication azathioprine. Imuran is manufactured by GlaxoSmithKline. Imuran is available as a tablet and as an injection. The tablet is available in strengths of 25 mg, 50 mg, and 100 mg. The injection is available in a strength of 100 mg/mL. Imuran is used to treat a variety of conditions, including⁚
  • Rheumatoid arthritis
  • Crohn's disease
  • Ulcerative colitis
  • Psoriasis
  • Lupus
  • Multiple sclerosis
  • Myasthenia gravis
  • Organ transplant rejection
Imuran is an immunosuppressant, which means that it suppresses the immune system. This can be helpful in treating conditions that are caused by an overactive immune system, such as rheumatoid arthritis and Crohn's disease. Imuran can also be used to prevent rejection of transplanted organs. Imuran is typically taken once or twice a day, with or without food. The dosage of Imuran will vary depending on the individual patient and the condition being treated. If you have any questions about the brand names of Imuran, talk to your doctor or pharmacist.

Generic name

The generic name of Imuran is azathioprine. Azathioprine is a medication that is used to suppress the immune system. It is used to treat a variety of conditions, including⁚
  • Rheumatoid arthritis
  • Crohn's disease
  • Ulcerative colitis
  • Psoriasis
  • Lupus
  • Multiple sclerosis
  • Myasthenia gravis
  • Organ transplant rejection
Azathioprine is available as a tablet and as an injection. The tablet is available in strengths of 25 mg, 50 mg, and 100 mg. The injection is available in a strength of 100 mg/mL. Azathioprine is typically taken once or twice a day, with or without food. The dosage of azathioprine will vary depending on the individual patient and the condition being treated. Azathioprine is a generic medication, which means that it is available from a variety of manufacturers. Generic medications are typically less expensive than brand-name medications. If you have any questions about the generic name of Imuran, talk to your doctor or pharmacist.

Drug class

Imuran belongs to a class of medications known as immunosuppressants. Immunosuppressants are medications that suppress the immune system. This can be helpful in treating conditions that are caused by an overactive immune system, such as rheumatoid arthritis and Crohn's disease. Imuran can also be used to prevent rejection of transplanted organs. Other medications in the immunosuppressant drug class include⁚
  • Methotrexate
  • Cyclosporine
  • Tacrolimus
  • Mycophenolate mofetil
  • Sirolimus
  • Everolimus
Immunosuppressants can be used to treat a variety of conditions, including⁚
  • Rheumatoid arthritis
  • Crohn's disease
  • Ulcerative colitis
  • Psoriasis
  • Lupus
  • Multiple sclerosis
  • Myasthenia gravis
  • Organ transplant rejection
Immunosuppressants can be effective in treating these conditions, but they can also have side effects. Some of the most common side effects of immunosuppressants include⁚
  • Nausea
  • Vomiting
  • Diarrhea
  • Hair loss
  • Skin rash
  • Increased risk of infection
If you are taking an immunosuppressant, it is important to talk to your doctor about the risks and benefits of the medication.

Route of administration

Imuran is available as a tablet and as an injection. The tablet is taken orally, with or without food. The injection is given intravenously (IV), which means that it is injected into a vein. The route of administration of Imuran will depend on the individual patient and the condition being treated. In general, the tablet is used for long-term treatment, while the injection is used for short-term treatment. If you are taking Imuran by mouth, it is important to take it at the same time each day. This will help to maintain a consistent level of medication in your body. If you are receiving Imuran by injection, the frequency of your injections will depend on the condition being treated. Your doctor will give you specific instructions on how often to receive your injections. It is important to follow your doctor's instructions carefully when taking Imuran. This will help to ensure that you are getting the most benefit from the medication and that you are avoiding any potential side effects. If you have any questions about the route of administration of Imuran, talk to your doctor or pharmacist.
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Imuran is available in two forms⁚
  • Tablet
  • Injection
The tablet is available in strengths of 25 mg, 50 mg, and 100 mg. The injection is available in a strength of 100 mg/mL. The tablet is taken orally, with or without food. The injection is given intravenously (IV), which means that it is injected into a vein. The form of Imuran that is best for you will depend on the individual patient and the condition being treated. In general, the tablet is used for long-term treatment, while the injection is used for short-term treatment. If you are taking Imuran by mouth, it is important to take it at the same time each day. This will help to maintain a consistent level of medication in your body. If you are receiving Imuran by injection, the frequency of your injections will depend on the condition being treated. Your doctor will give you specific instructions on how often to receive your injections; It is important to follow your doctor's instructions carefully when taking Imuran. This will help to ensure that you are getting the most benefit from the medication and that you are avoiding any potential side effects. If you have any questions about the form of Imuran that is best for you, talk to your doctor or pharmacist.
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Giving Information
Imuran is available in the following strengths⁚
  • Tablet⁚ 25 mg, 50 mg, 100 mg
  • Injection⁚ 100 mg/mL
The strength of Imuran that is best for you will depend on the individual patient and the condition being treated. Your doctor will determine the appropriate strength and dosage of Imuran for you. If you are taking Imuran by mouth, it is important to take it at the same time each day. This will help to maintain a consistent level of medication in your body. If you are receiving Imuran by injection, the frequency of your injections will depend on the condition being treated. Your doctor will give you specific instructions on how often to receive your injections. It is important to follow your doctor's instructions carefully when taking Imuran. This will help to ensure that you are getting the most benefit from the medication and that you are avoiding any potential side effects. If you have any questions about the strength of Imuran that is best for you, talk to your doctor or pharmacist.
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Support
Imuran is manufactured by GlaxoSmithKline. GlaxoSmithKline is a global pharmaceutical company headquartered in London, United Kingdom. GlaxoSmithKline develops, manufactures, and markets a wide range of prescription and over-the-counter medications, vaccines, and consumer healthcare products. Imuran is one of GlaxoSmithKline's most important products. It is used to treat a variety of conditions, including rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, lupus, multiple sclerosis, myasthenia gravis, and organ transplant rejection. GlaxoSmithKline has a long history of developing and manufacturing high-quality medications; The company is committed to research and innovation, and it invests heavily in new drug development. GlaxoSmithKline is also committed to patient safety, and it conducts rigorous clinical trials to ensure that its medications are safe and effective. If you are taking Imuran, you can be confident that you are taking a medication that is manufactured by a reputable and experienced pharmaceutical company. GlaxoSmithKline is committed to providing patients with high-quality medications that can improve their health and well-being.
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Imuran contains the following inactive ingredients⁚
  • Colloidal silicon dioxide
  • Lactose
  • Magnesium stearate
  • Povidone
  • Starch, corn
Inactive ingredients are used to help make the medication more stable, easier to manufacture, and more palatable. They do not have any therapeutic effect. If you have any allergies or sensitivities to any of the inactive ingredients in Imuran, talk to your doctor before taking the medication. Here is some additional information about the inactive ingredients in Imuran⁚
  • Colloidal silicon dioxide is a white, powdery substance that is used as an anti-caking agent. It is also used in a variety of other products, such as food, cosmetics, and toothpaste.
  • Lactose is a sugar that is found in milk. It is used as a filler in many medications.
  • Magnesium stearate is a white, waxy powder that is used as a lubricant. It is also used in a variety of other products, such as food, cosmetics, and plastics.
  • Povidone is a white, powdery substance that is used as a binder. It is also used in a variety of other products, such as food, cosmetics, and detergents.
  • Starch, corn is a white, powdery substance that is used as a filler. It is also used in a variety of other products, such as food, cosmetics, and paper.
If you have any questions about the inactive ingredients in Imuran, talk to your doctor or pharmacist.
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Warnings

Imuran can increase the risk of developing certain types of cancer, including skin cancer and lymphoma. The risk of cancer is small, but it is important to be aware of this potential side effect. Imuran can also increase the risk of developing serious infections. This is because Imuran suppresses the immune system, which makes it more difficult for the body to fight off infections. Imuran should be used with caution in patients who have a history of liver or kidney disease; Imuran can worsen these conditions, and it can also cause liver failure and kidney failure. Imuran should not be used in patients who are allergic to azathioprine or any of the other ingredients in the medication. Imuran should be used with caution in women who are pregnant or planning to become pregnant. Imuran can cause birth defects, and it can also pass into breast milk. Imuran should be used with caution in children under the age of 2 years. The safety and effectiveness of Imuran in children under the age of 2 years have not been established. If you are taking Imuran, it is important to talk to your doctor about the risks and benefits of the medication. Your doctor will monitor you closely for side effects and will make sure that you are taking the medication as directed.
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Precautions

Imuran should be used with caution in patients who have a history of liver or kidney disease. Imuran can worsen these conditions, and it can also cause liver failure and kidney failure. Imuran should also be used with caution in patients who have a history of bone marrow suppression. Imuran can suppress the bone marrow, which can lead to a decrease in the number of red blood cells, white blood cells, and platelets. Imuran should be used with caution in patients who are taking other medications that can suppress the bone marrow. These medications include methotrexate, leflunomide, and sulfasalazine. Imuran should be used with caution in women who are pregnant or planning to become pregnant. Imuran can cause birth defects, and it can also pass into breast milk. Imuran should be used with caution in children under the age of 2 years. The safety and effectiveness of Imuran in children under the age of 2 years have not been established. If you are taking Imuran, it is important to talk to your doctor about the risks and benefits of the medication. Your doctor will monitor you closely for side effects and will make sure that you are taking the medication as directed. Here are some additional precautions to keep in mind if you are taking Imuran⁚
  • Avoid contact with people who are sick.
  • Wash your hands frequently.
  • Get regular blood tests to monitor your blood counts.
  • Tell your doctor if you have any new or worsening symptoms, such as fever, chills, sore throat, or mouth sores.
By following these precautions, you can help to reduce your risk of side effects from Imuran.

Monitoring

Patients taking Imuran should be monitored closely by their doctor. This monitoring will help to ensure that the medication is working as intended and that the patient is not experiencing any serious side effects. The following tests may be performed to monitor patients taking Imuran⁚
  • Blood tests⁚ Blood tests can be used to monitor the patient's blood counts, liver function, and kidney function.
  • Urine tests⁚ Urine tests can be used to monitor the patient's kidney function.
  • Physical exams⁚ Physical exams can be used to check for any signs of side effects, such as skin rash or hair loss.
The frequency of monitoring will vary depending on the individual patient and the condition being treated. In general, patients taking Imuran will need to be monitored more frequently at the beginning of treatment and then less frequently as the condition improves. If you are taking Imuran, it is important to keep all of your appointments with your doctor. This will allow your doctor to monitor your progress and make sure that you are not experiencing any serious side effects. In addition to the tests listed above, your doctor may also recommend other tests to monitor your health while you are taking Imuran. These tests may include⁚
  • Chest X-ray
  • Electrocardiogram (ECG)
  • Eye exam
These tests can help your doctor to rule out any other conditions that may be causing your symptoms and to make sure that Imuran is not causing any serious side effects. If you have any questions about the monitoring of Imuran, talk to your doctor or pharmacist.
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  • Take Imuran with food to reduce the risk of nausea and vomiting.
  • Drink plenty of fluids while taking Imuran to help prevent kidney stones.
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  • Avoid alcohol while taking Imuran, as alcohol can increase the risk of side effects.
  • Tell your doctor if you are pregnant or planning to become pregnant. Imuran can cause birth defects.
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  • Tell your doctor if you are breastfeeding. Imuran can pass into breast milk.

    • Patient counseling

    Patients taking Imuran should be counseled on the following⁚
    • The risks and benefits of taking Imuran
    • The importance of taking Imuran exactly as prescribed
    • The potential side effects of Imuran
    • The importance of monitoring for side effects
    • The importance of following up with their doctor regularly
    Patients should be advised that Imuran can increase the risk of developing certain types of cancer, including skin cancer and lymphoma. The risk of cancer is small, but it is important to be aware of this potential side effect. Patients should also be advised that Imuran can increase the risk of developing serious infections. This is because Imuran suppresses the immune system, which makes it more difficult for the body to fight off infections. Patients should be instructed to take Imuran exactly as prescribed by their doctor. Skipping doses or taking too much Imuran can increase the risk of side effects. Patients should be advised to watch for signs of side effects, such as nausea, vomiting, diarrhea, hair loss, skin rash, and increased risk of infection. If any of these side effects occur, patients should contact their doctor promptly. Patients should be instructed to follow up with their doctor regularly. This will allow their doctor to monitor their progress and make sure that they are not experiencing any serious side effects. In addition to the information listed above, patients should also be counseled on the following⁚
    • The importance of avoiding contact with people who are sick
    • The importance of washing their hands frequently
    • The importance of getting regular blood tests to monitor their blood counts
    • The importance of telling their doctor if they have any new or worsening symptoms, such as fever, chills, sore throat, or mouth sores
    By following these instructions, patients can help to reduce their risk of side effects from Imuran and improve their overall health.

    Additional information

    Imuran is a powerful medication that can be effective in treating a variety of conditions. However, it is important to be aware of the risks and benefits of Imuran before taking it. If you are considering taking Imuran, talk to your doctor about the following⁚
    • Your medical history
    • Your current medications
    • Your lifestyle
    Your doctor will help you to weigh the risks and benefits of Imuran and decide if it is the right medication for you. Once you start taking Imuran, it is important to follow your doctor's instructions carefully. Take Imuran exactly as prescribed and do not skip any doses. If you have any questions or concerns about Imuran, talk to your doctor or pharmacist.
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    By following these tips, you can help to reduce your risk of side effects from Imuran and improve your overall health. 

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